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Byrd JC et al. A phase 1 and pharmacodynamic study of depsipeptide (FK228) in chronic lymphocytic leukemia and acute myeloid leukemia. Blood 2005;105(3):959-67. Abstract

Eisai. Preliminary efficacy update on EORTC phase III trial of Dacogen® versus supportive care in patients with myelodysplastic syndromes. Press release. July 1, 2008.

Fenaux P et al. Azacitidine (AZA) treatment prolongs overall survival (OS) in higher-risk MDS patients compared with conventional care regimens (CCR): Results of the AZA-001 phase III study. Proc ASH 2007;Abstract 817.

Gojo I et al. Phase 1 and pharmacologic study of MS-275, a histone deacetylase inhibitor, in adults with refractory and relapsed acute leukemias. Blood 2007;109(7):2781-90. Abstract

Gore SD et al. Combined methyltransferase/histone deacetylase inhibition with 5-azacitidine and MS-275 in patients with MDS, CMMoL and AML: Clinical response, histone acetylation and DNA damage. Proc ASH 2006;Abstract 517.

Kantarjian H et al. Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia. Blood 2007;109(1):52-7. Abstract

Kantarjian H et al. Decitabine improves patient outcomes in myelodysplastic syndromes: Results of a phase III randomized study. Cancer 2006;106(8):1794-803. Abstract

Klimek VM et al. Tolerability, pharmacodynamics, and pharmacokinetics studies of depsipeptide (romidepsin) in patients with acute myelogenous leukemia or advanced myelodysplastic syndromes. Clin Cancer Res 2008;14(3):826-32. Abstract

Raza A et al. Phase 2 study of lenalidomide in transfusion-dependent, low-risk, and
intermediate-1 risk myelodysplastic syndromes with karyotypes other than deletion 5q
. Blood 2008;111(1):86-93. Abstract

Sekeres MA et al. Preliminary results from a phase I study of Revlimid® (lenalidomide) in combination with Vidaza® (Azacitidine) in patients with advanced myelodysplastic syndromes (MDS). Proc ASH 2007;Abstract 1458.

 

 

 

 

 

 

 

 

 

 

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EDITOR
Neil Love, MD

INTERVIEWS

Steven D Gore, MD
- Select publications

Michael J Keating, MB, BS
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William I Bensinger, MD
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Fredrick B Hagemeister, MD
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